Test facility

Contract research

The test facility AGREA operates according to the principles contained in the DL March 17, 1995 No 194 (as amended) on the implementation of Dir 91/414/EEC on the marketing of plant protection products, as well as with the concepts of quality assurance for the correctness of the data applied to field trials on the efficacy of the products , as reported in the November 27, 1996 Interministerial Decree No. 37529th.

Efficacy studies

Experimental evidence of effectiveness are carried out according to the principles of Good Experimental Practice (GEP), as required by the European Plant Protection Organization (EPPO) under the "Guidelines for the Efficacy Evaluation of Plant Protection Products", vol.1 (March 1999), 2 (March 1997), 3 (December 1997), 4 (July 1998) and subsequent updates. In particular, for any test are always followed the guidelines No 181 "Conduct and reporting of Efficacy Evaluation Trials" and No 152 "Design and Analysis of Efficacy Evaluation Trials.
Field studies on the effects on beneficial organisms.
For evidence regarding the side effects of plant protection products on beneficial or non-target organisms, the test facility has as a reference standard methods of the International Organization for Pest (IOBC / WPRS) "Guidelines for testing the effects of pesticides on beneficials: description of test methods "(IOBC / WPRS, 1992), and the document" Guidance document on regulatory testing procedures for pesticides with non-target arthropods (SETAC, 1994) and "Guidelines to Evaluate Side-effects of plant protection products to non-target arthropods (IOBC / WPRS, 2000).

GLP

For the tests conducted according to GLP, the test facility AGREA is based on the guidelines of the OECD: ENV / JM / MONO (99) 22, ENV / MC / CHEM (98) 17, introduced into Italy by DL No.120 of 27-01-92 and subsequent updates. In any case, even for the efficacy trials, all forms is structured as shown in these guidelines.
- Organization of the facility --

The company has focused for years AGREA experimental agrarian third parties and is certified by Mi.PAF (Ministry of Agriculture and Forestry) to officially in Italy to conduct tests aimed at producing and efficacy data on residues of plant protection products on a European registration.

"European Organization for the Protection of Plants"
"International Organization for Pest"
"OECD (Organization for Economic Co-operation and Development)"
"Mi.P.A.F. (Ministry of Agriculture and Forestry) "

Principles of good experimental practice

The test facility operates according to the principles contained in the DL March 17, 1995 No 194 (as amended) concerning the implementation of Dir 91/414/EEC on the marketing of plant protection products, as well as with the concepts of quality assurance for the correctness of the data applied to the field efficacy trials products, as reported in the November 27, 1996 Interministerial Decree No. 37529th.
The tests conducted by AGREA can be summarized into three types:

In field trials on the efficacy of plant protection products in the following sectors:
SECTOR    
Aquatic Areas
Non-farm areas
Arboricultural
Herbaceous Crops
Forestry Crops
Medicinal and Aromatic Crops Ornamental plants
Horticulture Crops
Tropical Crops
Tanning seed
Storage post-harvest
TARGETS
Weeding
Entomology
Agricultural Microbiology
Nematology
Plant pathology
Agricultural Zoology
Seed Production
Vertebrates harmful
Growth regulators, activators and adjuvants
B field trials in addition to efficacy data, side effects of plant protection products on beneficial or non-target organisms;
C field tests in addition to efficacy data on the phytotoxicity of plant protection products.


The reference point for the qualitative tests described above are the principles of Good Experimental Practice (GEP), as provided by 'European Organization for Plant Protection Organization (EPPO) under the "Guidelines for the Efficacy Evaluation of Plant Protection Products", vol. 1 (March 1999), 2 (March 1997), 3 (December 1997). In particular, for any test are always followed the guidelines No 181 "Conduct and reporting of Efficacy Evaluation Trials" and No 152 "Design and Analysis of Efficacy Evaluation Trials.
For evidence regarding the side effects of plant protection products on beneficial or non-target organisms, the test facility has as a reference standard methods Organization 's International Pest (IOBC / WPRS) "Guidelines for testing the effects of pesticides on beneficials: description of test methods "(IOBC / WPRS, 1992), and the document" Guidance document on regulatory testing procedures for pesticides with non-target arthropods (SETAC, 1994).
AGREA has developed its own standard operating procedures (SOP), which refer, like the entire organization of the facility, as specified in the DL January 27, 1992 No 120 laying down rules on the implementation of Dir 88/320/EEC and 90/18/EEC with regard to inspection and verification of good laboratory practice and the guidelines of the 'OECD: ENV / JM / MONO (99) 22, ENV / MC / CHEM (98) 17.

Italian areas where Agrea carries out field trials:

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